Emerging Clinical Data Continues to Support CyberKnife Radiosurgery for the Treatment of Lung Cancer
Wednesday August 13, 8:30 am ET
The study, titled "Fractionated Stereotactic Body Radiation Therapy in the Treatment of Primary, Recurrent, and Metastatic Lung Tumors," was conducted at the University of Pittsburgh Medical Center (UPMC) in Pittsburgh, Pa., and followed three patient populations over an average 12 month period: 1) patients with primary stage I non-small cell lung cancer, 2) patients whose cancer recurred after it was surgically removed, and 3) patients with metastatic tumors in the lung. All patients were treated with CyberKnife radiosurgery over a three-day period as outpatients. These patients had limited treatment options because they were medically inoperable (unable to undergo surgery due to pre-existing medical conditions or prior surgery) or refused surgery.
The tumor control and survival outcomes were excellent in the first year following treatment. Control of tumor growth was achieved in 85 percent of primary cancer patients, 92 percent of recurrent lung cancer patients, and 62 percent of metastatic cancer patients during the first year of follow-up. This is drastically different from response rates for radiation therapy in this patient population, which are typically associated with poor local control and survival rates ranging from 10 to 30 percent at five-year follow-up, as noted within the study.
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